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1 . 2011

Assessment of the impact of GMO of plant origin on rat progeny development in 3 generations

AbstractThe publication presents the results of assessment of impact of genetically modified (GM) maize Liberty Link® on prenatal and postnatal development of progeny of 3 generations of Wistar rats. A total of 630 adult animals and 2837 pups were used in the experiment. The animals were divided into 5 groups which got the diets with inclusion of maize: the animals of the experimental group got the diet with the GM-maize, animals of the control group – with near isogenic conventional analogue of the GM-maize, animals of the 1st, 2nd and 3rd reference groups – conventional varieties of maize «ROSS 144 MV», «ROSS 197 MV», «Dokuchayevskaya 250 MV» respectively. The maize was included in the diet at maximum possible level not violating the balance of basic nutrients. Analysis of the data obtained during the study did not reveal any impact of GM-maize on rat progeny development.

Keywords:reproductive function, genetically modified (GM) foods, GM-maize, the progeny development of rats

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CHIEF EDITOR
CHIEF EDITOR
Viktor A. Tutelyan
Full Member of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Scientific Director of the Federal Research Centre of Nutrition, Biotechnology and Food Safety (Moscow, Russia)

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