The modification of methodological approaches for potential hazard identification of inadvertent chemicals in food

Abstract

The existing methodological approaches for hazard identification and selection of priority hazard contaminants in foodstuff for further health risk assessment and legislation (in case of need) do not represent the reasons of inclusion inadvertent chemical substances in a number of priority for health risk assessment. The absence both of complex assessment and potential hazard categories of contaminants do not allow to assess the urgency of health risk assessment. Thus, it’s advisable to expand the existing methodological approaches with the criteria of selection of hazard inadvertent chemical substances in food. The criteria allow for an integral assessment and further categorizing for health risk assessment and legislation.

The aim of the research was to develop the methodological approaches to selection of priority inadvertent chemical substances in foodstuff for risk analysis and legislation based on the integral assessment results.

Material and methods. Various methods of chemical analysis were applied for detection of potentially hazard chemical substances in foodstuff. The further hazard identification and selection of priority chemical substances has been based on suggested criteria and categories that complete existing methodology. The approbation of methodological approaches to integral assessment and categorizing has been carried out on milk.

Results and discussion. The potential hazard identification of inadvertent chemicals has been carried out using the complex of selection criteria. It was suggested to apply scores for calculation of integral score for further categorizing and selection of priority chemical substances (taking into account substances’ toxicity class and possibility of migration during cooking or formation during technological process, and from packing, and from food raw materials). 5 hazard chemicals in milk (2-furanmethanol, thallium, mevinphos, sulfotep, mephospholane) were defined as priority category as the result of approbation.

Conclusion. Integral assessment and categorizing of potential hazard of inadvertent chemicals in food applying basic and additional criteria taking into account natural content of the substances and their possibility of migration in food allow to assess the priority of health risk assessment and further hygienic legislation of the substances (in case if the risk level is inappropriate). During the approbation on the example of milk, 5 unintended substances that had potential hazard category I (high priority) were recommended for further risk assessment.

Keywords:inadvertent substances; milk; chemical hazard; risk assessment; category; toxicity; public health; foodstuff

Funding. The study had no sponsorship.

Conflict of interest. The authors declare no conflict of interest.

Contribution. Concept of the study – all authors; design of the study, collecting and processing the material, text writing – Suvorov D.V., Zelenkin S.E.; editing, approval of the final version of the article, responsibility for the integrity of all parts of the article – all authors.

For citation: Zaitseva N.V., Khotimchenko S.A., Shur P.Z., Suvorov D.V., Zelenkin S.E., Bessonov V.V. The modification of methodological approaches for potential hazard identification of inadvertent chemicals in food. Voprosy pitaniia [Problems of Nutrition]. 2023; 92 (1): 26–35. DOI: https://doi.org/10.33029/0042-8833-2023-92-1-26-35 (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Viktor A. Tutelyan
Full Member of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Scientific Director of the Federal Research Centre of Nutrition, Biotechnology and Food Safety (Moscow, Russia)

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